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Meta-analysis of valproate as maintenance therapy Authors: Macritchie KA et al. Title: Valproic acid, valproate, and divalproex in the maintenance treatment of bipolar disorder. Reference: Cochrane Database Syst Rev. 2001;(3):CD003196. Purpose: Meta-analysis of valproate as maintenance treatment. Study design: Meta-analysis. Follow up: Not applicable. Patients: Not applicable. Results: Available evidence is equivocal: conclusions about the efficacy of valproate versus placebo and lithium cannot be made. |