No treatment-emergent mania

Does not increase risk of treatment-emergent mania in depressed bipolar patients

During an 8-week trial of olanzapine and OFC in bipolar I depressed patients, OFC and olanzapine did not increase the risk of treatment-emergent mania.

GSK counterclaim:

Depression is consistently among the most frequently observed side effects with olanzapine maintenance treatment (Supporting data 3 and 4).