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 | | | | | | | Meta-analysis of valproate in acute mood episodes
Authors: Macritchie K, et al.
Title: Valproate for acute mood episodes in bipolar disorder.
Reference: Cochrane Database Syst Rev. 2003;(1):CD004052.
Purpose: Meta-analysis of valproate in acute mood episodes in bipolar disorder.
Study design: Meta-analysis.
Follow up: Not applicable.
Patients: Not applicable.
Treatment: Not applicable.
Results: There is consistent, yet limited, evidence to suggest that valproate is an efficacious treatment for acute mania. Valproate may be less effective than olanzapine, but may cause less sedation and weight gain.
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